From genes to proteins
|From genes to proteins|
|Biology Tutoring Wiki|
|Welcome to the tutoring wiki for BIOL 200. Here is where you'll find learning objectives and explanations for Unit 4 of BIOL 200.|
|Additional Tutoring Wikis|
- 1 Nuclear Function - RNA Transcription
- 1.1 Compare and contrast eukaryotic and prokaryotic transcription and translation, including TEM image interpretation.
- 1.2 Interpret an electron micrograph of eukaryotic transcription unit.
- 1.3 Explain with diagrams how different transcription units can be transcribed in different directions relative to the chromosome.
- 1.4 Discuss the importance and specificity of macromolecular interactions involved in transcription regulation by interpreting experimental evidence in eukaryotes.
- 2 Nuclear Function - RNA Processing
- 2.1 Compare and contrast the processing of mRNAs, transfer RNAs and ribosomal RNAs in eukaryotes.
- 2.2 Discuss experimental evidence for RNA splicing, e.g. evidence for intron removal from mRNA, specificity of splicing events as related to splice junction sequences and alternate splicing.
- 2.3 Describe the biosynthesis of ribosomes and the relation of these processes to nucleolar structure and function.
- 3 Genetic Code and Translation
- 3.1 Review the features of the genetic code and explain how they are related to the mechanisms of transcription and translation.
- 3.2 Explain the tRNA adapter systems - the role of coupling of tRNA to amino acids by amino acyl tRNA synthetases and the role of these enzymes in establishing the specificity of the genetic code.
- 3.3 Review (self-study) the events of translation including binding of mRNAs to ribosomes and protein factors in initiation, elongation and termination of translation.