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Hi:
I'm interested in the following two project and I have some questions and comments regarding each.
1. Longevity in China:
- What is the source of chronic data, and will the groups be consistent with that of the Harvard data groups?
- Is the subject interest mainly on religion or occupation? When the category gets too vast, we many not have enough data for each occupation to draw conclusion.
- There are many other factors other than occupation that affects the life longevity like district the people they live in. Ignoring these factors can cause the researcher to draw inaccurate conclusions. Either the factors are included or set to a constant (make every data be from a specific province)
2. DNA and Aging in Mice
- What are the criteria of being an "age mouse" and a "young mouse"? Is there another group between "young" and "old" mice?
- How are the mice selected? Are the age of the mice known? Do the mice spend their entire life in the lab?
- Are the experiments replicated or repeated?
- The mice need to be randomly assigned to different technicians to measure or draw samples in order to minimize the possible source of error in measurement.
Tracy Tien
Hello I am interested in the following two projects: 1. Micronutrient Powders
Questions: Was the sample of 300 children chosen equally from each of 4 districts? (75 children from each district?) Comments: Paired t-test might be used to compare effect of MNP on mean Hb level in treatment group and control group
2. DNA And AGE In Mice
Questions: How many samples will be used? How old are mice defined as aged mice? What is cell culture? Do you want to compare protein expression, various functions (migration, response to injury, etc.), levels of secreted proteins, and level of DNA compaction after treatment in young mice and aged mice, as well as comparison before the treatment? Which design of experiment used? Is the experiment conducted based on time series?
Comments: ANOVA may be used to compare effects of the treatment on young mice and aged mice.