Library:WD/ScholarlyCommunication/CycleOfScholarlyCommunication InsulinExample
The story of insulin
Michael Bliss (1982) [1] says in his book, "Insulin had not emerged out of a vacuum." A half-century of research by scientists around the world had laid the foundation for the discovery of insulin by Banting and Best at the University of Toronto.
By 1920, researchers had established that diabetes mellitus involves the body's inability to metabolize food, especially carbohydrates, and that it is the pancreas that is responsible for this metabolism. Many scientists speculated that it was an internal secretion produced by the islets of Langerhans in the pancreas that held the key to carbohydrate metabolism. So far, experiments to isolate the internal secretion and use it to treat diabetic patients had failed.