Course:PHAR501/RenalTubularAcidosis
| Renal Tubular Acidosis | |
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| PHAR 501 | |
| Section: | |
| Instructor: | Dr. Peter Loewen |
| Email: | peter.loewen@ubc.ca |
| Office: | PHRM 6624 |
| Office Hours: | |
| Class Schedule: | |
| Classroom: | 3101 |
| Important Course Pages | |
| Syllabus | |
| Lecture Notes | |
| Assignments | |
| Course Discussion | |
Renal Tubular Acidosis Assessment & Therapeutics
Instructor
Peter Loewen phone 604-827-1814
Pre-Session Objectives
PRIOR TO arriving at the session, participants should
- Be able to quickly interpret acid-base data using arterial blood gases.
- Name the hallmark signs of RTA and its consequences.
- Know what information is needed and how to calculate the urinary anion gap.
- Know which drugs can cause RTA.
Preparation for the session
- Read Sections 2 and 4.2 of Liamis G, Milionis HJ, Elisaf M. Pharmacologically-Induced Metabolic Acidosis. Drug Safety 2010;33:371-91.
- Retrieve PL's “Renal Tubular Acidosis: A Drug-Centric Perspective” PLOP
- Install “MedCalc” or “Mediquations”, or some other more specialized Acid/Base app on your iPhone/iPad/GalaxyS, or at a minimum, bring a calculator.
- Do the Self-assessment and review the Cases we'll discuss in class.
By the end of the session, and upon further learning and reflection students should be able to
- Recognize drug-related causes of RTA in a patient with possible RTA.
- Diagnose drug-associated RTA using by ordering and/or interpreting laboratory tests.
- Design a treatment and monitoring plan for a patient with RTA regardless of etiology.
Required Skills
- acid-base interpretation
- order and interpret lab tests
Further reading & Reference
- Clinical approach to renal tubular acidosis in adult patients. Int J Clin Pract 2011;65:350–60.
- Physiological Approach to Assessment of Acid–Base Disturbances. N Engl J Med 2014;371:1434–45.
- Everything you need to know about distal renal tubular acidosis in autoimmune disease. Rheumatol Int 2014;34:1037–45.
- Inherited Renal Acidoses-Physiol
- The Renal Tubular Acidoses-JRSM
- Renal tubular acidosis-the clinical entity-JASN
- Renal Tubular Acidosis-Pathophysiology and Diagnosis-ArchIM