| Date
|
Unit
|
Course Content
|
Readings
|
Instructor
|
| Lecture 1
|
Introduction
|
Course Introduction and overview
|
Chapter 1
|
SL, VM
|
| Lecture 2
|
Fundamental Cellular Biology and Genetics
|
Cell structure, chromosome structure, DNA replication
|
Chapter 2: pp 26-38
|
VM
|
| Lecture 3
|
|
Genetic mapping of traits
|
|
VM
|
| Lecture 4
|
|
RNA and protein synthesis, mutation causes and consequences
|
Chapter 2: pp 39-56
|
VM
|
| Lecture 5
|
|
Proteins as products
|
Chapter 4
|
VM
|
| Lecture 6
|
Enter the Genome Era
|
Genomics and systems biology concepts - think big
|
|
SL
|
| Lecture 7
|
|
Genomic sequencing and bioinformatics
|
Chapter 3: pp 68-71; 78-80
|
SL
|
| Lecture 8
|
|
Functional genomics - Expression profiling and gene discovery
|
|
SL
|
| Lecture 9
|
|
Molecular markers and genetic mapping
|
|
SL
|
| Lecture 10
|
Agricultural Biotechnology - Genetic Engineering
|
Molecular biology toolbox - Recombinant DNA technology
- practical features of vectors
- restriction enzymes, PCR, cloning PCR products
|
|
VM
|
| Lecture 11
|
|
Molecular biology toolbox - Control of gene expression in vivo
- promoters, promoter activity, altering gene expression levels
|
|
SL
|
| Lecture 12
|
|
CLass exercises in gene cloning
|
|
SL, VM
|
| Lecture 13
|
|
Genetic engineering in animals and plants
- expression constructs, gene delivery systems
|
|
SL
|
| Lecture 14
|
|
Assaying genetic engineering outcomes
- transgene copy number, expression levels, phenotype
- 'substantial equivalence' concept
|
|
SL
|
| Lecture 15
|
|
Review and discuss lectures 1-14
|
|
SL, VM
|
| Lecture 16
|
|
MIDTERM EXAM
|
|
|
| Lecture 17
|
|
Guest lecture on applications of natural plant products to pest control
- Dr. Murray Isman, Faculty of LFS
|
|
|
| Lecture 18
|
|
Guest lecture on biomarker technologies for agricultural food production and food safety monitoring
- Dr. Kevin Allen, Faculty of LFS
|
|
|
| Lecture 19
|
|
Student led discussion on non-GM biotechnology applications to food production
|
|
|
| Lecture 20
|
|
Genetic engineering - Application to fermentation product improvement
|
Chapter 5: pp 127-135; 141-144
|
VM
|
|
|
|
READING WEEK
|
|
|
| Lecture 21
|
|
Student led discussion on microbial biotech
|
|
|
| Lecture 22
|
|
Genetic engineering - Applications to agricultural crop improvement
|
Chapter 6: pp 156-170
|
SL
|
| Lecture 23
|
|
Student led discussion on crop biotech
|
|
|
| Lecture 24
|
|
Genetic engineering - Applications to livestock improvement
|
Chapter 7: pp 172-188
|
SL
|
| Lecture 25
|
|
Guest Lecture on biotech in livestock productivity
- Dr. Ronaldo Cerri, Faculty of LFS
|
|
|
| Lecture 26
|
|
Student led discussion on biotech in livestock production
|
|
|
| Lecture 27
|
|
Genetic engineering - Applications to aquaculture improvement
|
Chapter 10: pp 232-244; 245-259 (omit section on GFP)
|
VM
|
| Lecture 28
|
|
Guest lecture on aquaculture
- Dr. Robert Devlin, Centre for Aquatic Biotechnology Regulatory Research (CABRR), Fisheries and Oceans Canada, West Vancouver, BC
|
|
|
| Lecture 29
|
|
Student led discussion on aquaculture
|
|
|
| Lecture 30
|
|
Genetic engineering - Applications to bioremediation
|
Chapter 9: pp 209-230
|
VM
|
| Lecture 31
|
|
Guest lecture on biotechnology in bioremediation
- Dr. William Mohn, UBC Department of Microbiology and Immunology
|
|
|
| Lecture 32
|
|
Student led discussion on bioremediation
|
|
|
| Lecture 33
|
|
NO CLASS
|
|
|
| Lecture 34
|
|
Biotechnology policy 1 - Regulating biotechnology innovations
- Plants with Novel Traits, food labelling, health and environmental concerns
|
|
SL
|
| Lecture 35
|
|
Values and ethics in agricultural biotechnology, guest lecture
- Dr. Robin Downey, Genome British Columbia, Vancouver BC
|
Chapter 13: pp 325-342
|
|
| Lecture 36
|
|
Biotechnology policy 2 - Intellectual property issues associated with biotechnology innovations
- Dr. Emily Marden, UBC Sauder School of Business
|
|
|
| Lecture 37
|
|
Student led discussion on IP and safety in agricultural biotechnology
|
|
|
