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Summary
| Description | English: Salmonella Pathway: SipC is part of the TTSS and drives actin polymerization and actin-filament bundling; SopE activates Rho GTPases, fostering actin polimerization and membrane ruffle formation;SopB modulates inositol-polyphosphate metabolism, activating indirectly the same Rho GTPases as SopE; and SipA blocks the actin depolymerization factor cofilin, favoring also membrane ruffle formation [1]. SptP plays a role once the internalization has taken place, inactivating the Rho GTPases, inhibiting actin polymerization, and helping the closure of the plasma membrane over internalized bacteria |
| Date | 13 February 2015 () |
| File source | http://www.sciencedirect.com/science/article/pii/S0092867406001875 |
| Author | Pizarro-Cerda, J., & Cossart, P. (2006). Bacterial adhesion and entry into host cells. Cell, 124(4), 715-727. |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 08:17, 13 February 2015 | | 428 × 504 (244 KB) | WaldenCheung (talk | contribs) | User created page with UploadWizard |
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