File:Enterohemorrhagic Escherichia coli interacts with the colonic epithelium through the type III secretion system (T3SS).jpg
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Summary
| Description | English: The T3SS translocon includes the needle sheath protein EspA and pore proteins EspB and EspD. The translocon injects effector proteins into the host cytoplasm required for formation of the attaching and effacing lesion, including the translocated intimin receptor Tir. The EHEC protease EspP cleaves EspB, inhibiting this process. In contrast, the gut commensal B. thetaiotaomicron produces as-yet-unidentified proteases that cleave EspB and promote effector translocation and lesion formation. |
| Date | 26 February 2019 |
| File source | https://europepmc.org/article/med/30808700 |
| Author | Palmer LD, Skaar EP |
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| current | 05:56, 19 March 2022 | | 1,760 × 1,122 (251 KB) | AndyJia (talk | contribs) | Uploaded a work by Palmer LD, Skaar EP from https://europepmc.org/article/med/30808700 with UploadWizard |
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