File:Complement evasion strategies of Escherichia coli.jpg
Size of this preview: 800 × 587 pixels. Other resolution: 1,192 × 875 pixels.
Original file (1,192 × 875 pixels, file size: 417 KB, MIME type: image/jpeg)
Summary
Description | English: To overcome complement attack, E. coli has evolved diverse immune evasion strategies: (A) capsular polysaccharide may confer resistance to complement-mediated killing. (B) E. coli proteases such as Pic and extracellular serine protease P (EspP) may cleave complement components of all three pathways or, in the case of StcE, may recruit C1 inhibitor (C1-INH) to the surface of target cells, locally downregulating complement activation by the classical pathway. (C) cquisition of the soluble complement regulators FH and C4b-binding protein (C4BP) by outer membrane protein W (OmpW) and by outer membrane protein A (OmpA)/new lipoprotein I (NlpI) may allow downregulation of the alternative and the classical/lectin pathways of complement, respectively. |
Date | 20 April 2017 |
File source | https://www.frontiersin.org/articles/10.3389/fimmu.2017.00452/full |
Author | Afonso G. Abreu, Angela S. Barbosa |
Licensing
|
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 06:05, 19 March 2022 | 1,192 × 875 (417 KB) | AndyJia (talk | contribs) | Uploaded a work by Afonso G. Abreu, Angela S. Barbosa from https://www.frontiersin.org/articles/10.3389/fimmu.2017.00452/full with UploadWizard |
You cannot overwrite this file.
File usage
The following page uses this file: