Mutation

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Mutations

Define the different types of changes to DNA sequence

Predict effects of mutations in different locations of expression units in bacteria

Describe the origin of mutations through errors in replication, and damage to the DNA by UV light and selected chemical mutagens

Describe mechanisms that cells have for correcting damage to DNA (UV damage, nucleotide excision repair)

Estimate rates of mutations given simple examples

Devise procedures for finding mutations in bacteria given simple examples

Describe the effect mutations can have on the genotype and phenotype of a cell